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Even if the sleeping aid drug namely Ambien crosses the placenta, the use of this kind of drug appears not to affect the fetus according to the studies made in Washington. The said study was presented in the annual meeting of American Psychiatric Association. The subjects of the study are the pregnant women involved and included in the prospective study of the pharmacokinetic of psychotropic drugs during the pregnant stage of these women. They were being treated with Ambien during their child bearing days. There were maternal diagnoses made that used Structured Clinical Interview for DSM-IV. There were maternal and cord blood being extracted upon delivery.
The ratio of medication concentrate found in the umbilical cord and also the maternal plasma are being computed that would be the placental passage rate. When the umbilical cord concentration is less than 4.0 ng/mL. then it is the value needed for data analysis. This approach is quite conservative, erring towards overestimation of exposure to Ambien. When the said umbilical plasma concentrations and maternal concentrations were less than the detection limit then they are not included in the study.
The study compared the neonatal and obstetrical outcomes among pregnant women who have given birth after taking Ambien among women with outcomes that included the 45 women who were match for race, age, level of education and exposure to same classes of psychotropics. Statistically speaking, there is no significant difference found between the two groups in terms of neonatal and obstetrical outcomes. However, there were traces of preterm delivery and low-birth weights among women who are taking Ambien during their pregnancy. It is not yet proven whether Ambien exposure or sleep disturbance is connected with the use of this drug, according to Sandra Juric and her colleagues at Emory Universitys Womens Health Program in Atlanta.